Synthesis, structural and bioactivity studies of Cu(ii) complexes of polyamines, thiazole, imidazole and triazole ligands. Study of the structure-activity relationship
Abstract
Different series of CuII complexes were synthesized and presented according to their ligands: mixed-ligand complexes of Schiff dibases with 2a5mt [Cu(dienXX)(2a5mt)Y2], of Schiff monobases [Cu(dptaS)Y2], mixed-ligand complexes of dien and 2a2tzn ([Cu(dien)(2a2tzn)Y2]) or of Schiff bases and 2a2tzn ([Cu(dienXX)(2a2tzn)Y2]), of dien/dpta and tri- or tetrahalide ligands ([Cu(dien/dpta)(X)](XY2) and [Cu(dien)(X)]2(X2Y2), of Schiff bases and trihalide ligands ([Cu(dienΧX)(Y)(YZ2)]) and of dithiolates (i-MNT2- with amine ligands or thiazole/triazole derivatives). The new complexes were studied with C,H,N,S,Cu elemental analysis, IR and UV-Vis spectroscopy, magnetic and molar conductivity measurements. Theoretical studies were also performed; their results partly support the structures proposed although the minimization of energy was subjected to several restrictions. The X-ray analysis of representative complexes from each series confirms the proposed geometries. The biological (anticancer, ...
show more
Download full text in PDF format (8.06 MB)
(Available only to registered users)
|
All items in National Archive of Phd theses are protected by copyright.
|
Usage statistics
VIEWS
Concern the unique Ph.D. Thesis' views for the period 07/2018 - 07/2023.
Source: Google Analytics.
Source: Google Analytics.
ONLINE READER
Concern the online reader's opening for the period 07/2018 - 07/2023.
Source: Google Analytics.
Source: Google Analytics.
DOWNLOADS
Concern all downloads of this Ph.D. Thesis' digital file.
Source: National Archive of Ph.D. Theses.
Source: National Archive of Ph.D. Theses.
USERS
Concern all registered users of National Archive of Ph.D. Theses who have interacted with this Ph.D. Thesis. Mostly, it concerns downloads.
Source: National Archive of Ph.D. Theses.
Source: National Archive of Ph.D. Theses.