Ewing σάρκωμα της πυέλου

Περίληψη

Aναφέρουμε την εμπειρία μας σε ασθενείς με σάρκωμα Ewing πυέλου που έλαβαν θεραπεία στην Ογκολογική Μονάδα στο Βασιλικό Ορθοπεδικό Νοσοκομειο. Εξετασαμε αναδρομικά μια σειρά ασθενών με σάρκωμα μη μεταστατικόυ πυέλου του Ewing που αντιμετωπιστηκαν μεταξύ 1977 και 2009. Οι ασθενείς ταξινομήθηκαν σε τρεις ομάδες ανάλογα με την τοπική αγωγή

Περίληψη σε άλλη γλώσσα

We are reporting our experience on patients with pelvic Ewing’s Sarcoma treated in the Royal Orthopaedic Oncology Unit. We retrospectively reviewed a series of patients with non-metastatic pelvic Ewing’s sarcoma treated between 1977 and 2009. Patients were classified into three groups according to the local treatment received: Group 1: Radiotherapy-chemothrapy; Group 2: Surgery-chemotherapy and Group 3: Radiotherapy-surgery-chemotherapy. Recurrence free and overall survival rates were calculated using the Kaplan-Meier method. Influence of various factors (age at diagnosis, gender, tumour site and size, chemotherapy response, surgical margins and type of treatment) on survival was assessed with a logistic regression model. A total of 85 patients were treated with a mean follow-up of 65.8 months and mean tumour volume of 435ml. The 5-year survival for all patients was 40.7% decreased to 36.2% at 10 years. A significant prognostic factor identified was chemotherapy response only. There wa ...
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