Συμβολή στη μελέτη της χειρουργικής εξαίρεσης της ιδιοπαθούς επιαμφιβληστροειδικής μεμβράνης με σύγχρονη αφαίρεση του έσω αφοριστικού υμένα και την χρήση ινδοκυανίνης

Abstract

Purpose: To evaluate the anatomical and functional outcome in eyes with indocyanine green (ICG) assisted idiopathic epiretinal membrane (ERM) peeling by optical coherence tomography (OCT) and multifocal electroretinogram (MFERG). Design: Prospective, interventional, noncomparative case series. Methods: Twenty eyes of 20 patients with idiopathic ERM underwent pars plana vitrectomy and ICG assisted ERM and internal limiting membrane (ILM) removal. Visual acuity (VA), OCT and MFERG measurements were performed preoperatively and postoperatively at 1, 3, 6 and 12 months. Results: Best-corrected VA (BCVA) showed improvement of ?2 Snellen lines in 30% and 70% of our patients at the 1st and 12th postoperative month respectively. Mean VA increased from 20/100 preoperatively to 20/40 at 12 months. VA increased significantly at all postoperative examinations, compared to preoperative VA. Retinal thickness measured by OCT decreased significantly at all postoperative examinations. OCT mean values for foveal thickness dropped from 472.3 μm (±87.49) preoperatively, to 249.2 μm (±51.12) at 12 months. Preoperative MFERG values significantly improved compared only to the postoperative values at 12 months for both area 1 (p=0.0016) and area 2 (p=0.0081). Mean retinal response density increased from 4.37 nV/deg² (± 3.27) in area 1 and 3.61 nV/deg² (± 3.73) in area 2, to 10.08 nV/deg² (± 2.57) and 7.32 nV/deg² (± 2.80) respectively. OCT measurements and MFERG values did not correlate at any time.