ΕΝΔΕΙΑ ΒΙΤΑΜΙΝΗΣ Β12 ΜΕΤΑ ΥΦΟΛΙΚΗΝ ΓΑΣΤΡΕΚΤΟΜΗΝ

Abstract

Η ΜΕΤΡΗΣΙΣ ΤΗΣ ΒΙΤ. Β12 ΕΙΣ ΤΟΝ ΟΡΟΝ 79 ΥΠΟΣΤΑΝΤΩΝ ΥΦΟΛΙΚΗΝ ΓΑΣΤΡΕΚΤΟΜΗΝ ΚΑΙ 125 ΦΥΣΙΟΛΟΓΙΚΩΝ ΜΑΡΤΥΡΩΝ ΕΔΕΙΞΕΝ. 1.Η ΜΕΣΗ ΤΙΜΗ ΤΗΣ ΒΙΤ. Β12 ΕΙΣ ΤΟΝ ΟΡΟΝ ΤΩΝΓΑΣΤΡΕΚΤΟΜΗΘΕΝΤΩΝ (255PG/ML) ΗΤΟ ΠΕΡΙΠΟΥ ΤΟ 60% ΤΗΣ ΜΕΣΗΣ ΤΙΜΗΣ ΤΩΝ ΜΑΡΤΥΡΩΝ(493PG/ML).2.ΕΝΔΕΙΑ ΒΙΤ.Β12 ΑΝΕΥΡΕΘΗ ΕΙΣ 27 (34,1%) ΤΩΝ ΓΑΣΤΡΕΚΤΟΜΗΘΕΝΤΩΝ ΚΑΙ ΕΙΣ ΟΥΔΕΝΑ ΤΩΝ ΜΑΡΤΥΡΩΝ.3.ΤΟ ΠΛΕΙΣΤΟΝ (96,2%) ΤΩΝ ΕΧΟΝΤΩΝ ΠΑΘΟΛΟΓΙΚΑ ΕΠΙΠΕΔΑ ΒΙΤΑΜΙΝΗΣ ΕΙΣ ΤΟΝ ΟΡΟΝ ΗΣΑΝ ΑΤΟΜΑ ΧΕΙΡΟΥΡΓΗΘΕΝΤΑ ΠΡΟ 6 ΚΑΙ ΠΛΕΟΝ ΕΤΩΝ ΑΠΟ ΤΗΣ ΜΕΛΕΤΗΣ.4.Η ΕΝΔΕΙΑ ΒΙΤ.Β12 ΗΤΟ ΣΥΧΝΟΤΕΡΗ ΕΙΣ ΤΟΥΣ ΧΕΙΡΟΥΡΓΗΘΕΝΤΑΣ ΔΙ'ΕΛΚΟΣ ΣΤΟΜΑΧΟΥ (57,1%) ΕΝΑΝΤΙ ΤΩΝ ΧΕΙΡΟΥΡΓΗΘΕΝΤΩΝ ΔΙ'ΕΛΚΟΣ ΔΩΔΕΚΑΔΑΚΤΥΛΟΥ (29,2%).5.ΑΝΑΙΜΙΑ ΑΝΕΥΡΕΘΗ ΕΙΣ 62% ΤΩΝ Υ.Γ.ΚΑΙ ΕΙΣ 90,9% ΤΩΝ ΕΧΟΝΤΩΝ ΜΙΚΤΗΝ ΕΝΔΕΙΑΝ ΒΙΤ.Β12 ΚΑΙ ΣΙΔΗΡΟΥ.6.ΠΑΘΟΛΟΓΙΚΗ ΑΠΟΡΡΟΦΗΣΙΣ ΡΑΔΙΟΚΟΒΟΛΑΜΙΝΗΣ (SCHILLING TEST) ΑΝΕΥΡΕΘΗ ΕΙΣ 37,1% ΤΩΝ ΕΧΟΝΤΩΝ ΦΥΣΙΟΛΟΓΙΚΗΝ ΚΑΙ ΕΙΣ 57,2% ΜΕ ΠΑΘΟΛΟΓΙΚΗΝ Β12 ΕΙΣ ΤΟΝ ΟΡΟΝ.

SERUM VITAMIN B12 OF 79 PATIENTS WITH SUBTOTAL GASTRECTOMY AND 125 NORMAL SUBJECTS WAS STUDIED.ANALYSIS OF THE RESULTS REVEALED THE FOLLOWING.1.THE MEAN VALUE (225PG/ML) OF SERUM VITAMIN B12 OF THE SUBTOTAL GASTRECTOMY GROUP WAS THE 60% OF THE NORMAL SUBJECTS (493 PG/ML).2.VITAMIN B12 DEFICIENCY (LESS THAN 160PG/ML) WAS FOUND IN 27 (34,1%) OF THE PATIENTS.3.THE MAJORITY (96,2%) OF THE PATIENTS WITH VITAMIN B12 DEFICIENCY HAD BEEN OPERATED AT LEAST SIX YEARS BEFORE TH STUDY.4.VITAMIN B12 DEFICIENCY WAS MORE FREQUENT IN PATIENTS WHO HAD SUBTOTAL GASTRECTOMY BECAUSE OF GASTRIC UCLER (57,1%)),THAN THOSE WHO HAD BEEN OPERATED BECAUSE OF DUODENAL ULCER (29,2%).5.ANAEMIA WAS PRESENT IN 62% OF THE PATIENTS.HOWEVER 90,9% OF PATIENTS WITH COMBINED IRON AND VITAMIN B12 DEFICIENCY WERE ANAEMIC.6.VITAMIN B12 ABSORPTION AS ASSESSED USING THE SCHILLING TEST WAS SUBNORMAL IN 37,1% OF PATIENTS WITH NORMAL SERUM VITAMIN B12 LEVELS AND IN 57,2% OF PATIENTS WITH LOW SERUM VITAMINE B12 LEVELS.