Περίληψη σε άλλη γλώσσα
Background: Craniofacial malformations, as seen in Apert and Crouzon syndromes, may have an
immense impact not only on function and esthetics, but also on the psychosocial well-being of the
person affected.
Aims: To provide insight on the social life aspects of persons with Crouzon syndrome in
Sweden, during the transition from childhood to adulthood and as young adults. Furthermore, to
study the main facial and intraoral characteristics of persons with Apert or Crouzon syndrome,
the clinical manifestations that may be present in addition to the main syndromic features, and the
cranio-maxillofacial surgical treatment protocols followed. Finally, to investigate dental agenesis
and dental agenesis patterns of permanent teeth in persons with these syndromes.
Material and Methods: Firstly, interviews according to the qualitative method of
Grounded Theory were carried out. Eight persons with Crouzon syndrome participated. Then, 23
patients with Apert syndrome and 28 patients with ...
Background: Craniofacial malformations, as seen in Apert and Crouzon syndromes, may have an
immense impact not only on function and esthetics, but also on the psychosocial well-being of the
person affected.
Aims: To provide insight on the social life aspects of persons with Crouzon syndrome in
Sweden, during the transition from childhood to adulthood and as young adults. Furthermore, to
study the main facial and intraoral characteristics of persons with Apert or Crouzon syndrome,
the clinical manifestations that may be present in addition to the main syndromic features, and the
cranio-maxillofacial surgical treatment protocols followed. Finally, to investigate dental agenesis
and dental agenesis patterns of permanent teeth in persons with these syndromes.
Material and Methods: Firstly, interviews according to the qualitative method of
Grounded Theory were carried out. Eight persons with Crouzon syndrome participated. Then, 23
patients with Apert syndrome and 28 patients with Crouzon syndrome were evaluated for general
aspects, craniofacial aspects, dentoalveolar traits before and after the final orthognathic surgery,
types and timing of craniofacial surgical operations. Finally, dental agenesis and dental agenesis
patterns were studied in 26 persons with Crouzon syndrome and in 23 individuals with Apert
syndrome by evaluation of serial panoramic radiographs.
Results and Conclusions: The analysis of the interviews revealed that persons with
Crouzon syndrome had to face different obstacles when developing their self-image during the
transition from childhood to adulthood. Young adults with Crouzon syndrome tried to make the
best of their situation. Already from childhood, they developed various strategies that helped
them to cope with their lives. Mental disability, associated additional malformations, cleft palate,
and extensive lateral palatal swellings were more common in children with Apert syndrome. In
both syndromes, clinical findings included concave profile, negative overjet, posterior crossbites,
anterior openbite, and dental midline deviation, which were significantly improved in almost all
instances after the final combined orthodontic and orthognathic surgical treatment. The only
exception was the posterior crossbites, which were persisting in about half of the cases. Cranial
vault decompression and/or reshaping, midfacial and orbital advancement procedures, often in
conjunction with a mandibular set-back, were the most frequent craniofacial operations
performed in both of the syndromes investigated. The prevalence of agenesis for at least one
tooth was 42.3% for the patients with Crouzon syndrome. The dental agenesis patterns showed a
remarkable variability. The prevalence of agenesis for at least a tooth was 34.8% for the patients
with Apert syndrome. Symmetrical and repetitive dental agenesis patterns were identified.
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