ΟΙ ΜΙΚΡΟΣΚΟΠΙΚΕΣ ΑΛΛΟΙΩΣΕΙΣ ΤΟΥ ΠΛΑΚΟΥΝΤΑ ΣΤΗΝ ΠΕΡΙΓΕΝΝΗΤΙΚΗ ΑΣΦΥΞΙΑ ΤΩΝ ΝΕΟΓΝΩΝ

Abstract

IN THIS STUDY AN ATTEMPT TO FIND AND CLASSIFY THE MICROSCOPICAL CHANGES OF THE PLACENTA RELATED TO PERINATAL ASPHYXIA WAS MADE. PLACENTA HISTOLOGICAL FINDINGSWERE COMPARED WITH ACID-BASE STATUS OF BLOOD SAMPLES FROM UMBILICAL CORD AND WITH APGAR SCORE VALUES IN THE FIRST MINUTE OF LIFE. WE STUDIED 58 PLACENTAS TOGETHER WITH ESTIMATIONS OF ACID-BASE STATUS OF BLOOD SAMPLES TAKEN FROM THE UMBILICAL ARTERY AND VEIN OF NEONATES, BORN AT THE MATERNITY UNIT OF ALEXANDROUPOLIS GENERAL HOSPITAL. 25 PLACENTAS FROM NORMAL DELIVERIES WERE EXAMINED, AS WELL AS 33 FROM PREGNANCIES WITH PROBLEMS DURING THE GESTATIONAL PERIOD OR DURING DELIVERY. WE FOUND THAT NO SINGLE HISTOLOGICAL CHANGE OF THE PLACENTA IS RESPONSIBLE FOR THE FETAL INTRAUTERINE HYPOXIA, WHILE ALL OF THEM TOGETHER PLAY A ROLE FOR IT. THE TROPHOBLASTIC MEMBRANE THICKENING, THE INCREASE OF THE CYTOTROPHOBLASTIC CELLS AND THE DIMINISHED BLOOD FLOW IN THE VILLI, MUST BE THE CHANGES MORE RESPONSIBLE FOR THE INTRAUTERINE HYPOXIA. WE HAVE ALSO FOUND THAT APGAR SCORETOGETHER WITH THE DEGREE OF NEONATAL ACIDOSIS ARE THE BEST INDICATORS OF THE PERINATAL STATUS. FINALLY THE DISCREPANCY FOUND AMONG THE APGAR SCORE AND OF BLOOD SAMPLES AT THE FIRST MINUTE OF LIFE, MINIMIZES THE VALUE OF APGAR SCORE AS ARELIABLE INDEX OF THE PERINATAL STATUS.

ΣΚΟΠΟΣ ΤΗΣ ΕΡΓΑΣΙΑΣ ΑΥΤΗΣ ΕΙΝΑΙ Η ΑΝΑΖΗΤΗΣΗ ΚΑΙ ΤΑΞΙΝΟΜΗΣΗ ΤΩΝ ΧΑΡΑΚΤΗΡΙΣΤΙΚΩΝ ΜΙΚΡΟΣΚΟΠΙΚΩΝ ΑΛΛΟΙΩΣΕΩΝ ΤΟΥ ΠΛΑΚΟΥΝΤΑ ΠΟΥ ΣΥΝΔΕΟΝΤΑΙ ΠΕΡΙΣΣΟΤΕΡΟ ΜΕ ΤΗΝ ΠΕΡΙΓΕΝΝΗΤΙΚΗ ΑΣΦΥΞΙΑ ΤΟΥ ΝΕΟΓΝΟΥ ΚΑΙ Η ΣΥΣΧΕΤΙΣΗ ΤΟΥΣ ΜΕ ΤΗΝ ΟΞΕΟΒΑΣΙΚΗ ΙΣΟΡΡΟΠΙΑ ΣΤΟ ΑΙΜΑ ΤΟΥ ΟΜΦΑΛΙΟΥ ΛΩΡΟΥ ΚΑΙ ΤΗΝ ΒΑΘΜΟΛΟΓΙΑ ΚΑΤΑ APGAR ΣΤΟ ΠΡΩΤΟ ΛΕΠΤΟ ΤΗΣ ΖΩΗΣ, ΣΑΝ ΔΕΙΚΤΕΣ ΤΗΣ ΠΕΡΙΓΕΝΝΗΤΙΚΗΣ ΤΟΥ ΚΑΤΑΣΤΑΣΗΣ.